Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.59 |
| ▸ | PYGL | P06737 | 2/20 | 0.51 |
| ▸ | BACE1 | P56817 | 3/20 | 0.45 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CTSG | P08311 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10623978 | 0.84 | PYGL (0.48) | PYGLBACE1SLC6A11CYP1A2 | |
| SCHEMBL11023875 | 0.84 | CTSC (0.56) | PYGLBACE1SLC6A11CYP1A2NPC1 | |
| SCHEMBL10628562 | 0.84 | PYGL (0.48) | PYGLBACE1SLC6A11CYP1A2 | |
| SCHEMBL11028920 | 0.82 | PYGL (0.46) | PYGLBACE1SLC6A11CYP1A2NPC1 | |
| SCHEMBL8284265 | 0.82 | CYP1A2 (0.52) | PYGLCYP1A2NPC1RAB9AALPI | |
| SCHEMBL14570190 | 0.81 | PYGL (0.50) | PYGLCYP1A2NPC1RAB9AALPI | |
| SCHEMBL7442013 | 0.81 | CTRB1 (0.55) | PYGLCYP1A2LMNANPC1RAB9A | |
| SCHEMBL7434134 | 0.81 | CTRB1 (0.55) | PYGLCYP1A2LMNANPC1RAB9A | |
| SCHEMBL6558407 | 0.81 | ALDH1A1 (0.55) | ALDH1A1HTTNCOA1SMN1; SMN2NCOA3 | |
| SCHEMBL11028602 | 0.80 | MTNR1A (0.47) | PYGLBACE1SLC6A11LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4453003-A | ENZYME INHIBITORS, ANTIINFLAMMATORY AGENTS | UMEZAWA HAMAO (JP) | 1984-06-05 | — | — | US | disclosed |
| US-4391986-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediates therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1983-07-05 | — | — | US | disclosed |
| US-4281180-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediated therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1981-07-28 | — | — | US | disclosed |