Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 6/20 | 0.37 |
| ▸ | CA1 | P00915 | 4/20 | 0.37 |
| ▸ | CA4 | P22748 | 3/20 | 0.37 |
| ▸ | DPP4 | P27487 | 3/20 | 0.37 |
| ▸ | CA5A | P35218 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7435505 | 0.84 | PNMT (0.36) | ALDH1A1CA2CA1CA4DPP4 | |
| SCHEMBL7445352 | 0.80 | CA2 (0.40) | FFAR1ALDH1A1CA2MAPTHSD17B10 | |
| SCHEMBL10994694 | 0.80 | AKR1B1 (0.36) | FFAR1AKR1B1ALDH1A1CA2CA1 | |
| SCHEMBL7442226 | 0.78 | FFAR1 (0.35) | FFAR1AKR1B1ALDH1A1ADRA1ADAO | |
| SCHEMBL7438907 | 0.78 | CA2 (0.46) | FFAR1ALDH1A1CA2CA1MAPT | |
| SCHEMBL7436205 | 0.78 | CA2 (0.46) | FFAR1AKR1B1CA2MAPTLMNA | |
| SCHEMBL7436013 | 0.78 | LMNA (0.33) | ALDH1A1MAPTHSD17B10LMNASMN1; SMN2 | |
| SCHEMBL7436820 | 0.77 | LMNA (0.45) | FFAR1ALDH1A1ADRA1AMAPTUSP2 | |
| SCHEMBL7432523 | 0.77 | KMT2A (0.35) | ALDH1A1ADRA1AHCRTR2MAPTHSD17B10 | |
| SCHEMBL7439944 | 0.76 | KDM4E (0.35) | ALDH1A1CA2MAPTHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |