Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434182 | 0.84 | TAS1R3 (0.31) | LMNAMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL7445352 | 0.80 | CA2 (0.40) | LMNAMAPTSMN1; SMN2NPSR1KMT2A | |
| SCHEMBL10992132 | 0.80 | BACE1 (0.32) | MAPTSMN1; SMN2KMT2AALDH1A1CYP3A4 | |
| SCHEMBL7437298 | 0.78 | MLNR (0.32) | LMNAMAPTSMN1; SMN2NPSR1ADRB2 | |
| SCHEMBL7436205 | 0.78 | CA2 (0.46) | LMNAMAPTSMN1; SMN2NPSR1ADRB2 | |
| SCHEMBL7438907 | 0.78 | CA2 (0.46) | LMNAMAPTSMN1; SMN2NPSR1KMT2A | |
| SCHEMBL7440218 | 0.78 | FFAR1 (0.40) | LMNAMAPTSMN1; SMN2NPSR1HPGD | |
| SCHEMBL7436820 | 0.77 | LMNA (0.45) | LMNAMAPTSMN1; SMN2ADRB2ADRB1 | |
| SCHEMBL7432523 | 0.77 | KMT2A (0.35) | LMNAMAPTSMN1; SMN2NPSR1ADRB2 | |
| SCHEMBL7439944 | 0.76 | KDM4E (0.35) | LMNAMAPTSMN1; SMN2NPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |