Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ME2 | P23368 | 2/20 | 0.37 |
| ▸ | ME1 | P48163 | 2/20 | 0.37 |
| ▸ | ME3 | Q16798 | 2/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7501670 | 0.89 | LMNA (0.40) | HTR1AHTR7SIGMAR1LMNAMAPT | |
| SCHEMBL13779971 | 0.88 | KMT2A (0.43) | ALDH1A1TSHRTDP1POLBL3MBTL1 | |
| SCHEMBL7449469 | 0.85 | ALDH1A1 (0.38) | ALDH1A1TSHRME2ME1ME3 | |
| SCHEMBL7452641 | 0.79 | DRD2 (0.37) | KMT2AHTR7SIGMAR1NPSR1 | |
| SCHEMBL7663603 | 0.77 | HRH3 (0.36) | ALDH1A1TSHRKDM4E | |
| SCHEMBL7451579 | 0.77 | DRD2 (0.41) | TDP1POLBL3MBTL1KMT2A | |
| SCHEMBL216266 | 0.76 | FFAR1 (0.39) | NPSR1 | |
| Hydrochloric Acid SCHEMBL6625511 | 0.74 | FFAR1 (0.38) | KDM4ENPSR1 | |
| Hydrochloric Acid SCHEMBL1311654 | 0.74 | FFAR1 (0.38) | KDM4ENPSR1 | |
| SCHEMBL9555245 | 0.73 | ACE (0.48) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934293-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATING DISEASES ASSOCIATED WITH TRYPTASE ACTIVITY | ARRIS PHARMACEUTICAL CORPORATION (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998004537-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATING DISEASES ASSOCIATED WITH TRYPTASE ACTIVITY | ARRIS PHARMACEUTICAL CORPORATION (US) | 1998-02-05 | — | — | WO | disclosed |