Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | POLQ | O75417 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11760696 | 0.80 | SMN1; SMN2 (0.45) | LMNAPOLBALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7437685 | 0.80 | SMN1; SMN2 (0.50) | HSD11B1POLBALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL3254096 | 0.78 | LMNA (0.51) | LMNAALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL15150399 | 0.76 | LMNA (0.49) | LMNAALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL16415718 | 0.75 | LMNA (0.47) | LMNAPOLBALDH1A1KDM4EHSD17B10 | |
| SCHEMBL4840210 | 0.75 | POLB (0.46) | LMNAPOLBTP53SMN1; SMN2MEN1 | |
| SCHEMBL1120660 | 0.74 | LMNA (0.50) | LMNAPOLBALDH1A1KDM4EHSD17B10 | |
| SCHEMBL28291723 | 0.74 | LMNA (0.50) | LMNAHSD11B1POLBALDH1A1KDM4E | |
| SCHEMBL9069781 | 0.73 | LMNA (0.48) | LMNAPOLBKDM4EHSD17B10HTT | |
| SCHEMBL9304780 | 0.71 | ALDH1A1 (0.47) | LMNAHSD11B1POLBALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |