Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | PPID | Q08752 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7437685 | 0.82 | SMN1; SMN2 (0.50) | ALDH1A1POLBPPIDHSD11B1SMN1; SMN2 | |
| SCHEMBL18098741 | 0.80 | RIPK1 (0.50) | ALDH1A1L3MBTL1LMNARIPK1NPC1 | |
| SCHEMBL19139305 | 0.79 | MMP8 (0.51) | ALDH1A1POLBL3MBTL1LMNAHSD17B10 | |
| SCHEMBL8337648 | 0.75 | ALDH1A1 (0.57) | ALDH1A1POLBL3MBTL1PPIDLMNA | |
| Malonic Acid Diethyl Ester SCHEMBL11067701 | 0.75 | ALDH1A1 (0.57) | ALDH1A1POLBL3MBTL1PPIDLMNA | |
| SCHEMBL13539071 | 0.75 | ALDH1A1 (0.48) | ALDH1A1POLBL3MBTL1PPIDLMNA | |
| SCHEMBL3184733 | 0.74 | ALDH1A1 (0.54) | ALDH1A1POLBL3MBTL1PPIDLMNA | |
| SCHEMBL11190772 | 0.74 | RAB9A (0.72) | ALDH1A1POLBL3MBTL1PPIDLMNA | |
| SCHEMBL9037437 | 0.74 | MMP8 (0.52) | ALDH1A1POLBPPIDHSD11B1SMN1; SMN2 | |
| SCHEMBL19954207 | 0.73 | TSHR (0.52) | ALDH1A1LMNARIPK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0505379-B1 | MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER LTD (GB) | 1994-07-20 | — | — | EP | disclosed |
| US-5302595-A | Muscarinic receptor antagonists | PFIZER INC. (US) | 1994-04-12 | — | — | US | disclosed |
| US-5300516-A | Muscarinic receptor antagonists | PFIZER INC. (US) | 1994-04-05 | — | — | US | disclosed |
| US-5219871-A | MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1993-06-15 | — | — | US | disclosed |
| EP-0364123-B1 | MUSCARINIC RECEPTOR ANTAGONISTS | Pfizer Limited (GB) | 1991-06-12 | — | — | EP | disclosed |
| EP-0364123-A1 | Muscarinic receptor antagonists | Pfizer Limited (GB) | 1990-04-18 | — | — | EP | disclosed |