Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PPID | Q08752 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304780 | 0.82 | ALDH1A1 (0.47) | SMN1; SMN2HSD11B1POLBPPIDALDH1A1 | |
| SCHEMBL7440372 | 0.80 | LMNA (0.48) | SMN1; SMN2HSD11B1POLBALDH1A1MEN1 | |
| SCHEMBL12913142 | 0.74 | PIN1 (0.45) | SMN1; SMN2POLBALDH1A1MEN1KMT2A | |
| SCHEMBL28339016 | 0.74 | SMN1; SMN2 (0.46) | SMN1; SMN2POLBPPIDALDH1A1MEN1 | |
| SCHEMBL557889 | 0.73 | SMN1; SMN2 (0.55) | SMN1; SMN2PPIDALDH1A1MEN1KMT2A | |
| SCHEMBL5972547 | 0.73 | CYP2C19 (0.61) | SMN1; SMN2HSD11B1POLBPPIDALDH1A1 | |
| SCHEMBL21447568 | 0.73 | HSD11B1 (0.52) | SMN1; SMN2HSD11B1POLBPPIDALDH1A1 | |
| SCHEMBL8079696 | 0.73 | HSD11B1 (0.52) | SMN1; SMN2HSD11B1POLBPPIDALDH1A1 | |
| SCHEMBL8472209 | 0.72 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL313012 | 0.72 | POLB (0.55) | SMN1; SMN2HSD11B1POLBPPIDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |