Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1847594 | 0.80 | RAB9A (0.61) | RAB9AALDH1A1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL1851663 | 0.78 | NPC1 (0.58) | RAB9AALDH1A1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL4796310 | 0.76 | ALOX15 (0.44) | RAB9AALDH1A1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL7166995 | 0.74 | TLR9 (0.47) | RAB9AALDH1A1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL4967254 | 0.74 | ALDH1A1 (0.42) | RAB9AALDH1A1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL3891998 | 0.73 | HRH3 (0.53) | RAB9AALDH1A1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL321553 | 0.72 | ALOX15 (0.48) | RAB9AALDH1A1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL22515602 | 0.71 | ALOX15 (0.46) | RAB9AALDH1A1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL7165743 | 0.71 | RAB9A (0.58) | RAB9AALDH1A1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL7172987 | 0.69 | ALDH1A3 (0.42) | RAB9AALDH1A1KDM4ENPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609278-A1 | IMIDAZOPYRIDINES AND INDOLIZINES AS 5-HT 4 ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-08-10 | — | — | EP | disclosed |
| WO-1993008187-A1 | IMIDAZOPYRIDINES AND INDOLIZINES AS 5-HT4 ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-04-29 | — | — | WO | disclosed |