Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436434 | 0.78 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL7442288 | 0.76 | CYP2C19 (0.36) | DGAT1 | |
| SCHEMBL888296 | 0.69 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL31752 | 0.69 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL7448330 | 0.68 | — | — | |
| SCHEMBL7433559 | 0.67 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL12002565 | 0.66 | — | — | |
| SCHEMBL12135656 | 0.65 | MMP8 (0.42) | DGAT1 | |
| SCHEMBL15835198 | 0.65 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL7438458 | 0.64 | CYP4F2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6066666-A | OPTIONALLY N-SUBSTITUTED 3-MONO- AND DI-SUBSTITUTED 2-PYRROLIDINONES AND THIOLACTAM ANALOGS; TREAT SEIZURES, ANXIETY, AND ENHANCING 4-AMINOBUTYRIC ACID (GABA)-INDUCED CHLORIDE CURRENTS AT GABA RECEPTOR/IONOPHORE COMPLEX | WASHINGTON UNIVERSITY (US) | 2000-05-23 | — | — | US | disclosed |
| US-5776959-A | Anticonvulsant and anxiolytic lactam and thiolactam derivatives | WASHINGTON UNIVERSITY (US) | 1998-07-07 | — | — | US | disclosed |