Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440842 | 0.88 | CTSK (0.53) | CTSKMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7443191 | 0.85 | CTSK (0.54) | CTSKSMN1; SMN2CTSSALDH1A1 | |
| SCHEMBL7442355 | 0.84 | CTSK (0.71) | CTSKPPARGPPARACTSS | |
| SCHEMBL7438946 | 0.82 | MAPT (0.42) | CTSKMAPTALOX5CYP2D6CYP2C9 | |
| SCHEMBL1019102 | 0.80 | MAPT (0.55) | MAPTALOX5CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7449263 | 0.77 | OPRM1 (0.44) | MAPTALOX5CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7449281 | 0.77 | OPRM1 (0.44) | MAPTALOX5CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7433454 | 0.77 | CTSK (0.55) | CTSKPPARGPPARACTSS | |
| SCHEMBL7435956 | 0.77 | CTSK (0.55) | CTSKPPARGPPARACTSSALDH1A1 | |
| SCHEMBL2727573 | 0.77 | ACE (0.59) | CTSKMAPTALOX5NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187905-B1 | PEPTIDE COMPOUND WHICH INHIBITS VIRAL PROTEINASES; VIRICIDES FOR HEPATITIS C, HEPATITIS G, AND HUMAN GB VIRUSES | HOFFMANN-LA ROCHE INC. | 2001-02-13 | — | — | US | disclosed |