Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 11/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 7/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442355 | 0.88 | CTSK (0.71) | CTSKCTSSPPARGPPARACTSB | |
| SCHEMBL7433454 | 0.87 | CTSK (0.55) | CTSKCTSSPPARGPPARACTSB | |
| SCHEMBL7440842 | 0.86 | CTSK (0.53) | CTSKALDH1A1CTSSPPARGPPARA | |
| SCHEMBL7443191 | 0.81 | CTSK (0.54) | CTSKALDH1A1CTSS | |
| SCHEMBL7445430 | 0.80 | BACE1 (0.40) | CTSKABCB1ALDH1A1LMNACTSS | |
| SCHEMBL7449272 | 0.77 | CTSK (0.52) | CTSKALDH1A1CTSSPPARGPPARA | |
| SCHEMBL11957489 | 0.77 | L3MBTL1 (0.53) | EPHX2NR1H4GAA | |
| SCHEMBL7433111 | 0.76 | CTSK (0.49) | CTSKCTSSPPARGPPARACTSB | |
| SCHEMBL12839908 | 0.76 | EPHX2 (0.50) | CTSKCTSSEPHX2NR1H4PPARG | |
| SCHEMBL7445934 | 0.75 | CTSK (0.54) | CTSKCTSSCTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187905-B1 | PEPTIDE COMPOUND WHICH INHIBITS VIRAL PROTEINASES; VIRICIDES FOR HEPATITIS C, HEPATITIS G, AND HUMAN GB VIRUSES | HOFFMANN-LA ROCHE INC. | 2001-02-13 | — | — | US | disclosed |