Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 7/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7443120 | 0.87 | LMNA (0.41) | ALDH1A1KDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL7433758 | 0.86 | NPC1 (0.38) | ALDH1A1KDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL10998893 | 0.85 | ALDH1A1 (0.39) | ALDH1A1KDM4EGAALMNAMAPT | |
| SCHEMBL7436565 | 0.85 | ALDH1A1 (0.39) | ALDH1A1KDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL7435447 | 0.85 | LMNA (0.38) | ALDH1A1KDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL7435691 | 0.85 | GAA (0.41) | ALDH1A1KDM4EGAALMNAMAPT | |
| SCHEMBL7436658 | 0.83 | LMNA (0.39) | ALDH1A1KDM4EGAALMNAMAPT | |
| SCHEMBL7435907 | 0.83 | KDM4E (0.40) | ALDH1A1KDM4EGAALMNAMAPT | |
| SCHEMBL7439458 | 0.83 | MAPT (0.40) | ALDH1A1KDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL7434579 | 0.83 | CA2 (0.35) | ALDH1A1GAALMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |