Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 14/20 | 0.59 |
| ▸ | MMP3 | P08254 | 5/20 | 0.59 |
| ▸ | MMP13 | P45452 | 4/20 | 0.59 |
| ▸ | MMP9 | P14780 | 12/20 | 0.55 |
| ▸ | MMP1 | P03956 | 3/20 | 0.44 |
| ▸ | MMP8 | P22894 | 2/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | MMP25 | Q9NPA2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7507876 | 0.92 | MMP2 (0.60) | MMP2MMP3MMP13MMP9MMP1 | |
| SCHEMBL7499238 | 0.86 | MMP13 (0.59) | MMP2MMP3MMP13MMP9MMP1 | |
| SCHEMBL7516820 | 0.80 | MMP13 (0.54) | MMP2MMP3MMP13MMP9MMP1 | |
| SCHEMBL7449935 | 0.78 | MMP13 (0.60) | MMP2MMP3MMP13MMP9MMP1 | |
| SCHEMBL7447269 | 0.74 | MMP2 (1.00) | MMP2MMP3MMP13MMP9MMP1 | |
| SCHEMBL7507872 | 0.74 | MMP2 (0.88) | MMP2MMP3MMP13MMP9MMP1 | |
| SCHEMBL7451538 | 0.74 | F10 (0.48) | ALDH1A1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL7507252 | 0.73 | MMP13 (0.43) | MMP2MMP3MMP13MMP9MMP1 | |
| SCHEMBL7512865 | 0.73 | KMT2A (0.39) | MMP2MMP3MMP13MMP9MMP1 | |
| SCHEMBL7509277 | 0.73 | MMP2 (0.51) | MMP2MMP3MMP13MMP9MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002538136-A | — | — | 2002-11-12 | — | — | JP | claimed |
| EP-1165501-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2002-01-02 | — | — | EP | claimed |
| US-6197770-B1 | ENZYME INHIBITORS; ANTIARTHRITIC AGENTS; BONE DISORDERS | THE PROCTER & GAMBLE CO. | 2001-03-06 | — | — | US | claimed |
| WO-2000051975-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-08 | — | — | WO | claimed |
| EP-1165501-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2002-01-02 | — | — | EP | disclosed |
| US-6197770-B1 | ENZYME INHIBITORS; ANTIARTHRITIC AGENTS; BONE DISORDERS | THE PROCTER & GAMBLE CO. | 2001-03-06 | — | — | US | disclosed |
| WO-2000051975-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-08 | — | — | WO | disclosed |