Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 13/20 | 0.59 |
| ▸ | MMP2 | P08253 | 10/20 | 0.59 |
| ▸ | MMP1 | P03956 | 8/20 | 0.59 |
| ▸ | MMP3 | P08254 | 7/20 | 0.59 |
| ▸ | MMP9 | P14780 | 5/20 | 0.44 |
| ▸ | MMP8 | P22894 | 2/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | IL1RN | P18510 | 1/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449935 | 0.92 | MMP13 (0.60) | MMP13MMP2MMP1MMP3MMP9 | |
| SCHEMBL7447271 | 0.86 | MMP2 (0.59) | MMP13MMP2MMP1MMP3MMP9 | |
| SCHEMBL7516820 | 0.84 | MMP13 (0.54) | MMP13MMP2MMP1MMP3MMP9 | |
| SCHEMBL7507876 | 0.78 | MMP2 (0.60) | MMP13MMP2MMP1MMP3MMP9 | |
| SCHEMBL7507252 | 0.77 | MMP13 (0.43) | MMP13MMP2MMP1MMP3MMP9 | |
| SCHEMBL7502278 | 0.76 | MMP13 (0.55) | MMP13MMP2MMP1MMP3MMP9 | |
| SCHEMBL7903544 | 0.75 | MMP13 (0.57) | MMP13MMP2MMP1MMP3MMP9 | |
| SCHEMBL7508943 | 0.75 | MMP2 (0.53) | MMP13MMP2MMP1MMP3MMP9 | |
| SCHEMBL7499228 | 0.74 | MMP2 (1.00) | MMP13MMP2MMP1MMP3MMP9 | |
| SCHEMBL7516549 | 0.74 | MMP1 (0.49) | MMP13MMP2MMP1MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002538136-A | — | — | 2002-11-12 | — | — | JP | claimed |
| EP-1165501-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2002-01-02 | — | — | EP | claimed |
| US-6197770-B1 | ENZYME INHIBITORS; ANTIARTHRITIC AGENTS; BONE DISORDERS | THE PROCTER & GAMBLE CO. | 2001-03-06 | — | — | US | claimed |
| WO-2000051975-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-08 | — | — | WO | claimed |
| EP-1165501-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000051975-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-08 | — | — | WO | disclosed |