Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 3/20 | 0.38 |
| ▸ | MMP3 | P08254 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GRK2 | P25098 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7507876 | 0.82 | MMP2 (0.60) | KMT2AMEN1ALDH1A1MMP2MMP3 | |
| SCHEMBL7449935 | 0.82 | MMP13 (0.60) | KMT2AMEN1ALDH1A1MMP2MMP3 | |
| SCHEMBL7572580 | 0.78 | MMP13 (0.39) | MMP2MMP3MMP13MMP1MMP9 | |
| SCHEMBL7502964 | 0.77 | MMP13 (0.50) | ALDH1A1MMP2MMP3MMP13MMP1 | |
| SCHEMBL7502278 | 0.75 | MMP13 (0.55) | ALDH1A1MMP2MMP3MMP13MMP1 | |
| SCHEMBL7502706 | 0.75 | MMP13 (0.50) | MMP2MMP3MMP13MMP1MMP9 | |
| SCHEMBL7587417 | 0.75 | ALDH1A1 (0.41) | KMT2AMEN1ALDH1A1LMNATSHR | |
| SCHEMBL7499238 | 0.73 | MMP13 (0.59) | ALDH1A1MMP2MMP3MMP13MMP1 | |
| SCHEMBL7447271 | 0.73 | MMP2 (0.59) | KMT2AMEN1ALDH1A1MMP2MMP3 | |
| SCHEMBL7512859 | 0.71 | MMP13 (0.60) | MMP2MMP3MMP13MMP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165501-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2002-01-02 | — | — | EP | disclosed |
| US-6197770-B1 | ENZYME INHIBITORS; ANTIARTHRITIC AGENTS; BONE DISORDERS | THE PROCTER & GAMBLE CO. | 2001-03-06 | — | — | US | disclosed |
| WO-2000051975-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-08 | — | — | WO | disclosed |