Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLD1 | Q13393 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30547521 | 0.85 | DPP4 (0.43) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| SCHEMBL5314104 | 0.70 | PLD1 (0.49) | PLD1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL29462629 | 0.70 | PLD1 (0.68) | PLD1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL363383 | 0.70 | LMNA (0.45) | KDM4EALDH1A1HSD17B10ALOX5MEN1 | |
| SCHEMBL157489 | 0.70 | PLD1 (0.68) | PLD1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL230367 | 0.70 | PLD1 (0.68) | PLD1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL18228078 | 0.70 | PLD1 (0.68) | PLD1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL22326 | 0.69 | ALDH1A1 (0.69) | PLD1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL29390734 | 0.69 | ALDH1A1 (0.69) | PLD1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL21353591 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240208962-A1 | MICROBIOCIDAL QUINOLINE/QUINOXALINE BENZOTHIAZINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2024-06-27 | — | — | US | disclosed |
| US-12012399-B2 | Microbiocidal quinoline dihydro-(thiazine)oxazine derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2024-06-18 | — | — | US | disclosed |
| EP-4326710-A1 | MICROBIOCIDAL QUINOLINE/QUINOXALINE ISOQUINOLINE DERIVATIVES | Syngenta Crop Protection AG (CH) | 2024-02-28 | — | — | EP | disclosed |
| EP-4132924-B1 | MICROBIOCIDAL QUINOLINE DIHYDRO-(THIAZINE)OXAZINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2024-02-21 | — | — | EP | disclosed |
| EP-4132926-B1 | MICROBIOCIDAL QUINOLINE DIHYDRO-(THIAZINE)OXAZINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2024-02-21 | — | — | EP | disclosed |
| EP-4312556-A1 | MICROBIOCIDAL QUINOLINE/QUINOXALINE BENZOTHIAZINE DERIVATIVES | Syngenta Crop Protection AG (CH) | 2024-02-07 | — | — | EP | disclosed |
| CN-117241668-A | Microbiocidal quinoline/quinoxaline benzothiazine derivatives | 先正达农作物保护股份公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-117177963-A | Microbiocidal quinoline/quinoxaline isoquinoline derivatives | 先正达农作物保护股份公司 | 2023-12-05 | — | — | CN | disclosed |
| US-11744246-B2 | Preparation of mammalian oocyte for fertilization via a soluble human PH20 hyaluronidase polypeptide | SYNGENTA PARTICIPATIONS AG (CH) | 2023-09-05 | — | — | US | disclosed |
| WO-2023111215-A1 | MICROBIOCIDAL PYRIDINE-SUBSTITUTED BENZOTHIAZINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2023-06-22 | — | — | WO | disclosed |
| WO-2017029289-A1 | 1-HYDROXY-3H-2,1-BENZOXABOROLE DERIVATIVES AND THEIR USE AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-02-23 | — | — | WO | disclosed |
| WO-2016113313-A1 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-07-21 | — | — | WO | disclosed |
| WO-2016113303-A1 | MICROBIOCIDAL BENZOXABOROLES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-07-21 | — | — | WO | disclosed |
| WO-2016071239-A1 | NOVEL FUNGICIDAL PYRIDYLAMIDINES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-05-12 | — | — | WO | disclosed |
| WO-2016016118-A1 | MICROBIOCIDAL IMIDAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-02-04 | — | — | WO | disclosed |
| WO-2015162268-A1 | MICROBIOCIDAL IMIDAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-10-29 | — | — | WO | disclosed |
| WO-2015162271-A1 | MICROBIOCIDAL IMIDAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-10-29 | — | — | WO | disclosed |
| WO-2015162269-A1 | MICROBIOCIDAL IMIDAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-10-29 | — | — | WO | disclosed |
| US-5330994-A | Antidepressants, anxiolytic agents | WARNER-LAMBERT COMPANY (US) | 1994-07-19 | — | — | US | disclosed |
| WO-1993019062-A1 | TETRAHYDROPYRIDINE ISOXAZOLINE DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 1993-09-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12012399-B2 | Microbiocidal quinoline dihydro-(thiazine)oxazine derivatives | TLR1, TLR5, IDO1 | PLD1 620/4885KDM4E 2885/4885ALDH1A1 312/4885 |
| US-20240208962-A1 | MICROBIOCIDAL QUINOLINE/QUINOXALINE BENZOTHIAZINE DERIVATIVES | IFNG, IRF3, MAVS | PLD1 768/4885KDM4E 1541/4885ALDH1A1 1076/4885 |
| US-11744246-B2 | Preparation of mammalian oocyte for fertilization via a soluble human PH20 hyaluronidase polypeptide | PHF20, FUCA1, ZP1 | PLD1 536/4885KDM4E 4050/4885ALDH1A1 1241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.