Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | CTSC | P53634 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7435853 | 0.85 | SLC1A1 (0.48) | SLC1A1MMP3MMP2LTA4HCA12 | |
| SCHEMBL8700502 | 0.80 | CA12 (0.51) | SLC1A1MMP3MMP2CA12CA7 | |
| SCHEMBL27680894 | 0.77 | KMT2A (0.51) | CA12CA7CA9CA14TSHR | |
| SCHEMBL27680893 | 0.77 | KMT2A (0.51) | CA12CA7CA9CA14TSHR | |
| SCHEMBL7447989 | 0.77 | LMNA (0.53) | CA12CA7CA9CA14TSHR | |
| SCHEMBL4845257 | 0.76 | KMT2A (0.49) | METAP2METAP1TSHRALDH1A1 | |
| SCHEMBL1859677 | 0.76 | SMN1; SMN2 (0.50) | TSHRALDH1A1 | |
| SCHEMBL1859940 | 0.76 | GRIK1 (0.51) | MMP3MMP2TSHRLMNA | |
| SCHEMBL1841055 | 0.75 | LTA4H (0.53) | LTA4HLNPEPERAP2METAP2METAP1 | |
| SCHEMBL276649 | 0.75 | LTA4H (0.53) | LTA4HLNPEPERAP2METAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5096925-A | N-substituted butyramide derivatives | CIBA-GEIGY CORPORATION (US) | 1992-03-17 | — | — | US | disclosed |
| US-4939261-A | ANALGESICS, ANTIDEPRESSANTS, HYPOTENSIVE AGENTS, NEUROLEPTIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1990-07-03 | — | — | US | disclosed |
| EP-0185079-B1 | N-SUBSTITUTED BUTYRAMIDE DERIVATIVES | CIBA-GEIGY AG (CH) | 1988-10-19 | — | — | EP | disclosed |
| EP-0185079-A1 | — | CIBA GEIGY AG | 1986-06-25 | — | — | EP | disclosed |
| WO-1986000066-A1 | N-SUBSTITUTED BUTYRAMIDE DERIVATIVES | CIBA-GEIGY AG (CH) | 1986-01-03 | — | — | WO | disclosed |