Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MMP14 | P50281 | 2/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8096459 | 0.84 | MEN1 (0.49) | MEN1KMT2AMMP14ADAMTS5MAPT | |
| SCHEMBL8109659 | 0.78 | MEN1 (0.52) | MEN1KMT2AMMP14ADAMTS5MAPT | |
| SCHEMBL28895576 | 0.72 | MEN1 (0.56) | MEN1KMT2AMMP14ADAMTS5MAPT | |
| SCHEMBL4675462 | 0.72 | HDAC1 (0.41) | MEN1KMT2AMMP14ADAMTS5MAPT | |
| SCHEMBL4675456 | 0.72 | HDAC1 (0.41) | MEN1KMT2AMMP14ADAMTS5MAPT | |
| SCHEMBL8550694 | 0.68 | MEN1 (0.48) | MEN1KMT2AMMP14ADAMTS5MAPT | |
| SCHEMBL4673636 | 0.68 | MMP14 (0.51) | MEN1KMT2AMMP14ADAMTS5MAPT | |
| SCHEMBL4673959 | 0.68 | GRM5 (0.41) | MEN1KMT2AMMP14ADAMTS5MAPT | |
| SCHEMBL7445507 | 0.67 | GRM5 (0.43) | MEN1KMT2AMMP14ADAMTS5MAPT | |
| SCHEMBL7448674 | 0.67 | MAPT (0.53) | MEN1KMT2AMMP14ADAMTS5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0958287-A1 | SULFAMIDE-METALLOPROTEASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 1999-11-24 | — | — | EP | disclosed |
| WO-1998032748-A1 | SULFAMIDE-METALLOPROTEASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 1998-07-30 | — | — | WO | disclosed |