Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 5/20 | 0.45 |
| ▸ | DRD2 | P14416 | 4/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7448172 | 0.84 | MEN1 (0.43) | MEN1KMT2AMAPTMMP14ADAMTS5 | |
| SCHEMBL8109659 | 0.84 | MEN1 (0.52) | MEN1KMT2AMAPTMMP14ADAMTS5 | |
| SCHEMBL28895576 | 0.76 | MEN1 (0.56) | MEN1KMT2AMAPTMMP14ADAMTS5 | |
| SCHEMBL7445507 | 0.74 | GRM5 (0.43) | MEN1KMT2AMAPTMMP14ADAMTS5 | |
| SCHEMBL7448674 | 0.72 | MAPT (0.53) | MEN1KMT2AMAPTMMP14ADAMTS5 | |
| SCHEMBL4757515 | 0.72 | MEN1 (0.51) | MEN1KMT2AMAPTMMP14ADAMTS5 | |
| SCHEMBL8550694 | 0.71 | MEN1 (0.48) | MEN1KMT2AMAPTMMP14ADAMTS5 | |
| SCHEMBL4673636 | 0.71 | MMP14 (0.51) | MEN1KMT2AMAPTMMP14ADAMTS5 | |
| SCHEMBL4677143 | 0.70 | SMN1; SMN2 (0.45) | MEN1KMT2AMAPTMMP14ADAMTS5 | |
| SCHEMBL4677141 | 0.70 | SMN1; SMN2 (0.45) | MEN1KMT2AMAPTMMP14ADAMTS5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143744-A | Sulfamide-metalloprotease inhibitors | SYNTEX (U.S.A.) INC. (US) | 2000-11-07 | — | — | US | disclosed |
| US-5998412-A | ANTIARTHRITIC AGENTS; OSTEOPOROSIS | SYNTEX (U.S.A.) INC. (US) | 1999-12-07 | — | — | US | disclosed |