Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL284168 | 0.86 | EPHX1 (0.46) | EPHX1ITGB3ITGA2BACHEALDH1A1 | |
| SCHEMBL480292 | 0.86 | EPHX1 (0.46) | EPHX1ITGB3ITGA2BACHEALDH1A1 | |
| SCHEMBL2332506 | 0.85 | TGFBR1 (0.47) | EPHX1ACHEALDH1A1 | |
| SCHEMBL283288 | 0.85 | ITGB3 (0.46) | EPHX1ITGB3ITGA2BACHEALDH1A1 | |
| SCHEMBL7382637 | 0.85 | NOD1 (0.48) | EPHX1ITGB3ITGA2BACHECTSK | |
| SCHEMBL5765667 | 0.85 | TGFBR1 (0.47) | EPHX1ACHEALDH1A1 | |
| SCHEMBL1840799 | 0.85 | TGFBR1 (0.47) | EPHX1ACHEALDH1A1 | |
| SCHEMBL3655323 | 0.85 | ITGB3 (0.46) | EPHX1ITGB3ITGA2BACHEALDH1A1 | |
| SCHEMBL284211 | 0.85 | ITGB3 (0.46) | EPHX1ITGB3ITGA2BACHEALDH1A1 | |
| SCHEMBL1077922 | 0.85 | NOD1 (0.48) | EPHX1ITGB3ITGA2BACHECTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140895-A2 | THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040576-A2 | THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-07-13 | — | — | WO | disclosed |