Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MPL | P40238 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | VCP | P55072 | 3/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6181728 | 0.85 | ALOX5 (0.43) | NAMPTSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL7449186 | 0.74 | GRM1 (0.35) | NAMPTSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL7486512 | 0.73 | CTSB (0.50) | NAMPTSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL7490691 | 0.72 | CTSB (0.51) | NAMPTSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL6184068 | 0.72 | CTSL (0.49) | NAMPTSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL6270008 | 0.71 | SMN1; SMN2 (0.57) | NAMPTSMN1; SMN2HPGDSNPC1RAB9A | |
| SCHEMBL6181726 | 0.71 | CTSL (0.56) | NAMPTSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL6265313 | 0.67 | CTSK (0.41) | NAMPTSMN1; SMN2HPGDSVCPROCK1 | |
| Trifluoroacetic Acid SCHEMBL6186180 | 0.66 | MPL (0.39) | NAMPTSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL6447376 | 0.66 | ITGB1 (0.48) | CAPN1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002539192-A | — | — | 2002-11-19 | — | — | JP | claimed |
| EP-1161415-A2 | N-CYANOMETHYLAMIDES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-12-12 | — | — | EP | claimed |
| WO-2000055126-A2 | N-CYANOMETHYLAMIDES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | claimed |