Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
| ▸ | KLK1 | P06870 | 1/20 | 0.30 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7451026 | 0.96 | ALDH1A1 (0.36) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7447916 | 0.93 | RAB9A (0.38) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7447469 | 0.90 | NPC1 (0.36) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7452254 | 0.90 | RAB9A (0.38) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7447757 | 0.88 | NPC1 (0.34) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL7451196 | 0.88 | RAB9A (0.38) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7446035 | 0.86 | NPC1 (0.34) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7446732 | 0.85 | NPC1 (0.33) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7445643 | 0.85 | NPC1 (0.35) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7415098 | 0.82 | RAB9A (0.41) | NPC1ALDH1A1LMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095025-A2 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM KG (DE) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000001704-A2 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-01-13 | — | — | WO | disclosed |