Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | PYGL | P06737 | 1/20 | 0.30 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.30 |
| ▸ | TNKS | O95271 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7448750 | 0.80 | PDE2A (0.36) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7449396 | 0.79 | MAPT (0.37) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7413025 | 0.74 | F2 (0.43) | NPC1RAB9A | |
| SCHEMBL7447136 | 0.72 | ALDH1A1 (0.37) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7454489 | 0.70 | NPC1 (0.38) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7446445 | 0.70 | NPC1 (0.38) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL9901721 | 0.70 | NQO2 (0.46) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7394949 | 0.69 | ALDH1A1 (0.43) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7421109 | 0.69 | NPC1 (0.37) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7444335 | 0.69 | MAPT (0.41) | NPC1ALDH1A1LMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095025-A2 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM KG (DE) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000001704-A2 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-01-13 | — | — | WO | disclosed |