Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.69 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.69 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.65 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.65 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.65 |
| ▸ | GNAI3 | P08754 | 4/20 | 0.58 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.58 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.58 |
| ▸ | F2R | P25116 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30014708 | 0.83 | ITGB3 (0.68) | ITGB3ITGA2BTPSAB1TPSD1TPSG1 | |
| SCHEMBL7452238 | 0.83 | ITGB3 (0.63) | ITGB3ITGA2BTPSAB1TPSD1TPSG1 | |
| SCHEMBL4470355 | 0.80 | ITGB3 (0.58) | ITGB3ITGA2BTPSAB1TPSD1TPSG1 | |
| SCHEMBL7446733 | 0.79 | TPSAB1 (1.00) | ITGB3ITGA2BTPSAB1TPSD1TPSG1 | |
| SCHEMBL11489205 | 0.78 | ITGB3 (0.60) | ITGB3ITGA2BTPSAB1TPSD1TPSG1 | |
| SCHEMBL7447602 | 0.78 | TPSAB1 (0.56) | ITGB3ITGA2BTPSAB1TPSD1TPSG1 | |
| SCHEMBL22291286 | 0.78 | ITGB3 (0.46) | ITGB3ITGA2BTPSAB1TPSD1TPSG1 | |
| SCHEMBL14303380 | 0.77 | ITGB3 (0.59) | ITGB3ITGA2BTPSAB1TPSD1TPSG1 | |
| SCHEMBL381083 | 0.76 | ITGB3 (0.66) | ITGB3ITGA2BTPSAB1TPSD1TPSG1 | |
| SCHEMBL8278505 | 0.76 | ITGB3 (0.61) | ITGB3ITGA2BTPSAB1TPSD1TPSG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934293-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATING DISEASES ASSOCIATED WITH TRYPTASE ACTIVITY | ARRIS PHARMACEUTICAL CORPORATION (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998004537-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATING DISEASES ASSOCIATED WITH TRYPTASE ACTIVITY | ARRIS PHARMACEUTICAL CORPORATION (US) | 1998-02-05 | — | — | WO | disclosed |