Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.40 |
| ▸ | ITGAV | P06756 | 3/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CLPP | Q16740 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7458234 | 0.93 | ITGB1 (0.47) | ITGB3ITGAVITGB1ITGA2BITGB5 | |
| SCHEMBL7378843 | 0.93 | ITGB1 (0.47) | ITGB3ITGAVITGB1ITGA2BITGB5 | |
| SCHEMBL7375077 | 0.87 | RHOC (0.39) | ITGB3ITGAVNOS3NOS1NOS2 | |
| SCHEMBL7451733 | 0.81 | FPR2 (0.45) | ITGB3ITGAVITGB1ITGA2BITGB5 | |
| SCHEMBL7454545 | 0.81 | FPR2 (0.45) | ITGB3ITGAVITGB1ITGA2BITGB5 | |
| SCHEMBL7378850 | 0.80 | ITGB1 (0.46) | ITGB3ITGAVITGB1ITGA2BITGB5 | |
| SCHEMBL7458333 | 0.80 | ITGB1 (0.46) | ITGB3ITGAVITGB1ITGA2BITGB5 | |
| SCHEMBL241017 | 0.78 | ITGB3 (0.59) | ITGB3ITGAVITGB1ITGA2BITGB5 | |
| SCHEMBL241018 | 0.78 | ITGB3 (0.59) | ITGB3ITGAVITGB1ITGA2BITGB5 | |
| SCHEMBL7377736 | 0.78 | ITGB1 (0.49) | ITGB3ITGAVITGB1ITGA2BITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891325-B1 | PARA-SUBSTITUTED PHENYLPROPANOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | SEARLE & CO (US) | 2002-02-06 | — | — | EP | claimed |