Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | TDP2 | O95551 | 3/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYBB | P04839 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.37 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27528567 | 0.84 | ATM (0.40) | MAPTTDP2HPGDKMT2AGAA | |
| SCHEMBL9449446 | 0.81 | PTPN1 (0.40) | TDP2 | |
| SCHEMBL27362455 | 0.77 | TDP2 (0.34) | TDP2CRBN | |
| SCHEMBL8923640 | 0.76 | TSHR (0.35) | NPC1TDP2KMT2AMEN1 | |
| SCHEMBL27357288 | 0.76 | TDP2 (0.30) | TDP2CRBN | |
| SCHEMBL14521036 | 0.72 | CRBN (0.60) | MAPTNPC1RAB9ATDP2HSD17B1 | |
| SCHEMBL21135535 | 0.70 | MAPT (0.54) | MAPTNPC1RAB9AHSD17B1HPGD | |
| SCHEMBL688076 | 0.69 | EPHX2 (0.56) | MAPTNPC1RAB9AKMT2AGAA | |
| SCHEMBL7349547 | 0.69 | MAPT (0.49) | MAPTNPC1RAB9ATDP2HSD17B1 | |
| SCHEMBL74499 | 0.69 | AHR (0.45) | MAPTNPC1TDP2HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5234924-A | Hypotensive agents | ADIR ET COMPAGNIE (FR) | 1993-08-10 | — | — | US | disclosed |