Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | ADA | P00813 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449545 | 1.00 | KMT2A (0.40) | KMT2ARENPSMB5ADAKDM4E | |
| SCHEMBL7448681 | 0.90 | KMT2A (0.40) | KMT2AHPGD | |
| SCHEMBL7452291 | 0.88 | MEN1 (0.37) | KMT2AALDH1A1HPGD | |
| SCHEMBL7448880 | 0.87 | PTGER1 (0.37) | PSMB5HPGDCTSLCTSBCTSS | |
| SCHEMBL7449950 | 0.87 | ALDH1A1 (0.41) | KMT2AKDM4EALDH1A1HPGDCASP1 | |
| SCHEMBL7450779 | 0.87 | CTSG (0.37) | ADAHPGDCTSLCTSBCTSS | |
| SCHEMBL7827665 | 0.86 | APLNR (0.37) | KMT2A | |
| SCHEMBL7837015 | 0.86 | ADA (0.47) | KMT2AADAMETAP2METAP1 | |
| SCHEMBL7449901 | 0.86 | ATM (0.36) | KMT2AALDH1A1HPGD | |
| SCHEMBL7453353 | 0.84 | CNR1 (0.38) | KMT2APSMB5HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001026605-A2 | IMMUNOSUPPRESSIVE COMPOSITION CONTAINING IL-2 INHIBITOR AND AN ADENOSINE DEAMINASE INHIBITOR | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-19 | — | — | WO | disclosed |