Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 5/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | CHUK | O15111 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442844 | 0.82 | HTR6 (0.40) | HTR6L3MBTL1TLR9TLR8TLR7 | |
| SCHEMBL7444087 | 0.76 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL7808827 | 0.72 | L3MBTL1 (0.41) | HTR6L3MBTL1MEN1KMT2ASLC6A4 | |
| SCHEMBL4674205 | 0.68 | HTR6 (0.51) | HTR6SLC6A4HTR1AKCNH2GABRP | |
| SCHEMBL7843747 | 0.68 | HTR6 (0.50) | HTR6L3MBTL1MEN1KMT2ASLC6A4 | |
| SCHEMBL7855641 | 0.68 | L3MBTL1 (0.39) | HTR6L3MBTL1MEN1KMT2ASLC6A4 | |
| SCHEMBL2270899 | 0.67 | SLC6A4 (0.67) | HTR6SLC6A4HTR2AHTR1ADRD1 | |
| SCHEMBL30545930 | 0.65 | CHUK (0.68) | L3MBTL1MEN1KMT2ACHUKAR | |
| SCHEMBL606784 | 0.65 | CHUK (0.68) | L3MBTL1MEN1KMT2ACHUKAR | |
| SCHEMBL29402283 | 0.65 | CHUK (0.68) | L3MBTL1MEN1KMT2ACHUKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0958287-A1 | SULFAMIDE-METALLOPROTEASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 1999-11-24 | — | — | EP | disclosed |
| WO-1998032748-A1 | SULFAMIDE-METALLOPROTEASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 1998-07-30 | — | — | WO | disclosed |