Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 10/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 10/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 10/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CHUK | O15111 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.33 |
| ▸ | GABRE | P78334 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7453129 | 0.85 | HTR6 (0.41) | HTR6TLR9TLR8TLR7SLC6A4 | |
| SCHEMBL7450455 | 0.82 | HTR6 (0.40) | HTR6TLR9TLR8TLR7L3MBTL1 | |
| SCHEMBL7448879 | 0.80 | FNTA (0.41) | — | |
| SCHEMBL4670879 | 0.71 | HTR6 (0.45) | HTR6GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL7444565 | 0.68 | BRD3 (0.50) | TLR8TLR7 | |
| SCHEMBL7808827 | 0.64 | L3MBTL1 (0.41) | HTR6L3MBTL1MEN1KMT2ACHUK | |
| SCHEMBL7843747 | 0.64 | HTR6 (0.50) | HTR6L3MBTL1MEN1KMT2ASLC6A4 | |
| SCHEMBL6618224 | 0.62 | BCHE (0.38) | L3MBTL1MEN1KMT2ASLC6A4 | |
| SCHEMBL7855641 | 0.62 | L3MBTL1 (0.39) | HTR6L3MBTL1MEN1KMT2ACHUK | |
| SCHEMBL735680 | 0.62 | CHUK (0.48) | L3MBTL1MEN1KMT2ACHUKSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0958287-A1 | SULFAMIDE-METALLOPROTEASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 1999-11-24 | — | — | EP | disclosed |
| WO-1998032748-A1 | SULFAMIDE-METALLOPROTEASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 1998-07-30 | — | — | WO | disclosed |