Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 9/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 9/20 | 0.42 |
| ▸ | PRKCA | P17252 | 4/20 | 0.42 |
| ▸ | PRKCB | P05771 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 7/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7448850 | 0.91 | NR1H2 (0.41) | NR1H2ADRB1NR1H3HTR6 | |
| SCHEMBL7457394 | 0.78 | HTR6 (0.38) | NR1H2NR1H3HTR6 | |
| SCHEMBL3454917 | 0.75 | HTR6 (0.65) | ADRB1HTR6 | |
| Hydrochloric Acid SCHEMBL11370762 | 0.74 | HTR6 (0.63) | ADRB1HTR6 | |
| SCHEMBL7453354 | 0.71 | ALDH1A1 (0.53) | — | |
| SCHEMBL4256879 | 0.70 | LMNA (0.47) | NR1H2NR1H3HTR6 | |
| SCHEMBL17519321 | 0.70 | NR1H2 (0.56) | NR1H2ADRB1NR1H3 | |
| SCHEMBL2301921 | 0.70 | LMNA (0.64) | HTR6 | |
| Hydrochloric Acid SCHEMBL28327327 | 0.70 | NR1H2 (0.55) | NR1H2ADRB1NR1H3 | |
| Hydrochloric Acid SCHEMBL28144205 | 0.70 | NR1H2 (0.55) | NR1H2ADRB1NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1240141-A1 | NEW MODULATORS OF DOPAMINE NEUROTRANSMISSION | A. Carlsson Research AB (SE) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001046144-A1 | NEW MODULATORS OF DOPAMINE NEUROTRANSMISSION | A. CARLSSON RESEARCH AB (SE) | 2001-06-28 | — | — | WO | disclosed |