Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 18/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 16/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7450604 | 0.78 | PRKCQ (0.42) | HTR6NR1H2NR1H3 | |
| SCHEMBL7448850 | 0.75 | NR1H2 (0.41) | HTR6NR1H2NR1H3 | |
| SCHEMBL3454917 | 0.74 | HTR6 (0.65) | HTR6 | |
| Hydrochloric Acid SCHEMBL11370762 | 0.73 | HTR6 (0.63) | HTR6 | |
| SCHEMBL7134126 | 0.70 | HSD11B1 (0.40) | NR1H2 | |
| SCHEMBL7134133 | 0.70 | HSD11B1 (0.40) | NR1H2 | |
| SCHEMBL2301921 | 0.69 | LMNA (0.64) | HTR6 | |
| SCHEMBL19214303 | 0.67 | DRD2 (0.51) | HTR6NR1H2NR1H3 | |
| SCHEMBL8270700 | 0.67 | LMNA (0.57) | HTR6 | |
| SCHEMBL21442524 | 0.67 | DRD2 (0.51) | HTR6NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1240141-A1 | NEW MODULATORS OF DOPAMINE NEUROTRANSMISSION | A. Carlsson Research AB (SE) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001046144-A1 | NEW MODULATORS OF DOPAMINE NEUROTRANSMISSION | A. CARLSSON RESEARCH AB (SE) | 2001-06-28 | — | — | WO | disclosed |