Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 3/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.43 |
| ▸ | PI4KA | P42356 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.43 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 3/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 3/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 3/20 | 0.42 |
| ▸ | PRKX | P51817 | 3/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.42 |
| ▸ | PAK4 | O96013 | 2/20 | 0.42 |
| ▸ | PIM1 | P11309 | 2/20 | 0.42 |
| ▸ | PRKACA | P17612 | 2/20 | 0.42 |
| ▸ | CLK2 | P49760 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3260282 | 0.90 | BTK (0.47) | RETLRRK2PI4KAXDHPI4K2B | |
| SCHEMBL3260275 | 0.75 | AURKA (0.46) | RETLRRK2PI4KAXDHPI4K2B | |
| SCHEMBL9851131 | 0.71 | G6PD (0.65) | MAPK1G6PDCASP7CASP6LMNA | |
| SCHEMBL3677097 | 0.70 | L3MBTL1 (0.46) | RETLRRK2PI4KAXDHPI4K2B | |
| SCHEMBL12590750 | 0.69 | XDH (0.53) | RETLRRK2PI4KAXDHPI4K2B | |
| SCHEMBL31121562 | 0.69 | XDH (0.53) | RETLRRK2PI4KAXDHPI4K2B | |
| SCHEMBL29761062 | 0.69 | TRPA1 (0.47) | RETLRRK2PI4KAXDHPI4K2B | |
| SCHEMBL19575560 | 0.68 | RET (0.40) | RETLRRK2PI4KAXDHPI4K2B | |
| SCHEMBL15477778 | 0.68 | G6PD (0.49) | MAPK1G6PDCASP7CASP6LMNA | |
| SCHEMBL17744802 | 0.68 | G6PD (0.61) | MAPK1G6PDCASP7CASP6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138356-B2 | Chemical inhibitors of inhibitors of differentiation | Angiogeney, Inc. (US) | 2012-03-20 | — | — | US | disclosed |