Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.33 |
| ▸ | FEN1 | P39748 | 2/20 | 0.33 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 2/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7107797 | 0.84 | SMN1; SMN2 (0.36) | ALDH1A1POLBHPGDHSD17B10MAPK1 | |
| SCHEMBL7105859 | 0.79 | CLK4 (0.35) | ALDH1A1CYP2D6CYP19A1CYP3A4 | |
| SCHEMBL7455246 | 0.74 | METAP2 (0.36) | ALDH1A1POLBHPGDNR4A1ESR2 | |
| SCHEMBL7447660 | 0.74 | ADRA1A (0.36) | ALDH1A1POLBHPGDNR4A1ESR2 | |
| SCHEMBL7447711 | 0.72 | ALDH1A1 (0.38) | ALDH1A1POLBHPGDNR4A1ESR2 | |
| SCHEMBL3525749 | 0.69 | MEN1 (0.39) | ALDH1A1POLBHPGDHSD17B10MAPK1 | |
| SCHEMBL7454492 | 0.68 | ADRA1A (0.36) | ALDH1A1POLBHPGDNR4A1ESR2 | |
| SCHEMBL8101802 | 0.68 | ADRA1A (0.34) | ALDH1A1POLBHPGDNR4A1ESR2 | |
| SCHEMBL17591534 | 0.67 | HSD17B10 (0.55) | ALDH1A1POLBHPGDNR4A1ESR2 | |
| SCHEMBL30636365 | 0.67 | HSD17B10 (0.55) | ALDH1A1POLBHPGDNR4A1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1104403-A1 | HYDROXY PIPECOLATE HYDROXAMIC ACID DERIVATIVES AS MMP INHIBITORS | Pfizer Products Inc. (US) | 2001-06-06 | — | — | EP | disclosed |
| WO-2000009485-A1 | HYDROXY PIPECOLATE HYDROXAMIC ACID DERIVATIVES AS MMP INHIBITORS | PFIZER PRODUCTS INC. (US) | 2000-02-24 | — | — | WO | disclosed |