Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 11/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7452045 | 0.99 | MGLL (0.54) | MGLLMEN1KMT2ALMNATP53 | |
| SCHEMBL7453044 | 0.91 | MGLL (0.55) | MGLLMEN1KMT2ALMNATP53 | |
| SCHEMBL7450265 | 0.80 | KMT2A (0.48) | MEN1KMT2ALMNAMAPTL3MBTL1 | |
| SCHEMBL14282295 | 0.79 | MGLL (0.68) | MGLLMEN1KMT2ALMNATP53 | |
| SCHEMBL7456487 | 0.79 | LMNA (0.42) | MEN1KMT2ALMNAMAPTL3MBTL1 | |
| SCHEMBL7633019 | 0.78 | MGLL (0.56) | MGLLMEN1KMT2ALMNATP53 | |
| SCHEMBL14282294 | 0.78 | MGLL (0.67) | MGLLMEN1KMT2ALMNATP53 | |
| SCHEMBL7511899 | 0.78 | KMT2A (0.58) | MEN1KMT2ALMNAMAPT | |
| SCHEMBL7457660 | 0.76 | MGLL (0.54) | MGLLMEN1KMT2ALMNATP53 | |
| SCHEMBL14391641 | 0.75 | POLB (0.67) | MGLLMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237868-A1 | HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEINASE (MMP) INHIBITORS | Darwin Discovery Limited (GB) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001044189-A1 | HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEINASE (MMP) INHIBITORS | DARWIN DISCOVERY LIMITED (GB) | 2001-06-21 | — | — | WO | disclosed |