Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23163299 | 0.80 | MAPT (0.41) | POLBTDP1L3MBTL1MAPTPIN1 | |
| SCHEMBL9554649 | 0.76 | ADORA2B (0.38) | L3MBTL1MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL16732173 | 0.74 | PIN1 (0.50) | POLBTDP1MAPTPIN1ALDH1A1 | |
| SCHEMBL9554861 | 0.70 | L3MBTL1 (0.51) | POLBTDP1L3MBTL1MAPTPIN1 | |
| SCHEMBL12390099 | 0.70 | MAPT (0.38) | POLBTDP1L3MBTL1MAPTALDH1A1 | |
| SCHEMBL4236408 | 0.69 | L3MBTL1 (0.50) | POLBTDP1L3MBTL1MAPTPIN1 | |
| SCHEMBL74549 | 0.69 | MAPT (0.44) | POLBTDP1L3MBTL1MAPTALDH1A1 | |
| SCHEMBL10517438 | 0.69 | ALDH1A1 (0.38) | POLBTDP1L3MBTL1MAPTALDH1A1 | |
| SCHEMBL28125649 | 0.68 | RAB9A (0.47) | POLBTDP1L3MBTL1MAPTALDH1A1 | |
| SCHEMBL1414713 | 0.68 | NPC1 (0.47) | TDP1L3MBTL1MAPTALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250517-A | Hypotensive and cardiotonic agents; cardiac insufficiency | HOFFMANN-LA ROCHE INC. (US) | 1993-10-05 | — | — | US | disclosed |