Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 2/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
| ▸ | ALPL | P05186 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | ALPG | P10696 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7458484 | 0.84 | CYP3A4 (0.41) | ESR1ESR2CYP3A4TDP1CES2 | |
| SCHEMBL686789 | 0.81 | CES2 (0.44) | TDP1CES2CES1TSHRAKR1B1 | |
| Ammonia Solution, Strong SCHEMBL17670041 | 0.79 | CES2 (0.42) | TDP1CES2CES1TSHRAKR1B1 | |
| Hydrochloric Acid SCHEMBL10915156 | 0.79 | CES2 (0.42) | TDP1CES2CES1TSHRAKR1B1 | |
| Phosphonic Acid SCHEMBL7871109 | 0.79 | TDP1 (0.67) | ESR1ESR2CYP3A4TDP1CES2 | |
| SCHEMBL21112093 | 0.78 | NOS1 (0.31) | ESR1ESR2CES2CES1 | |
| SCHEMBL21993580 | 0.78 | LMNA (0.52) | GAAABCC4LMNATSHRPTGS1 | |
| Phosphonic Acid SCHEMBL15511192 | 0.77 | TDP1 (0.63) | ESR1ESR2CYP3A4TDP1CES2 | |
| Phosphonic Acid SCHEMBL15511191 | 0.77 | TDP1 (0.63) | ESR1ESR2CYP3A4TDP1CES2 | |
| Phosphonic Acid SCHEMBL15510587 | 0.77 | TDP1 (0.63) | ESR1ESR2CYP3A4TDP1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807637-B1 | Process for the preparation of tertiary phosphanes containing phosphinate or phosphonate groups and novel tertiary phosphanes containing phosphinate groups | CELANESE CHEM EUROPE GMBH (DE) | 2002-02-13 | — | — | EP | claimed |
| US-5801263-A | Process for preparing tertiary phosphines containing phosphinate or phosphonate groups, and novel tertiary phosphines containing phosphinate groups | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-09-01 | — | — | US | claimed |
| EP-0807637-A1 | Process for the preparation of tertiary phosphanes containing phosphinate or phosphonate groups and novel tertiary phosphanes containing phosphinate groups | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-19 | — | — | EP | claimed |
| EP-0807637-B1 | Process for the preparation of tertiary phosphanes containing phosphinate or phosphonate groups and novel tertiary phosphanes containing phosphinate groups | CELANESE CHEM EUROPE GMBH (DE) | 2002-02-13 | — | — | EP | disclosed |
| EP-0842145-B1 | METHOD OF CARRYING OUT CROSS-COUPLING REACTIONS | CLARIANT GMBH (DE) | 2000-07-19 | — | — | EP | disclosed |
| US-5801263-A | Process for preparing tertiary phosphines containing phosphinate or phosphonate groups, and novel tertiary phosphines containing phosphinate groups | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-09-01 | — | — | US | disclosed |
| US-5756804-A | Homogeneous process for carrying out cross-coupling reactions | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-05-26 | — | — | US | disclosed |
| EP-0842145-A1 | METHOD OF CARRYING OUT CROSS-COUPLING REACTIONS | Clariant GmbH (DE) | 1998-05-20 | — | — | EP | disclosed |
| EP-0807637-A1 | Process for the preparation of tertiary phosphanes containing phosphinate or phosphonate groups and novel tertiary phosphanes containing phosphinate groups | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-19 | — | — | EP | disclosed |
| WO-1997005104-A1 | METHOD OF CARRYING OUT CROSS-COUPLING REACTIONS | CLARIANT GMBH (DE) | 1997-02-13 | — | — | WO | disclosed |