Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7457935 | 0.95 | CCR2 (0.37) | ALDH1A1TDP1DPP8DPP9SIGMAR1 | |
| SCHEMBL7463906 | 0.92 | ALDH1A1 (0.33) | ALDH1A1TDP1DPP8DPP9SIGMAR1 | |
| SCHEMBL7456796 | 0.91 | POLB (0.34) | ALDH1A1TDP1DPP8DPP9SIGMAR1 | |
| SCHEMBL7454533 | 0.89 | PLCG1 (0.33) | ALDH1A1TDP1SIGMAR1CCR2MAPT | |
| SCHEMBL7453875 | 0.86 | CCR2 (0.35) | ALDH1A1DPP8DPP9SIGMAR1CCR2 | |
| SCHEMBL7456405 | 0.85 | TDP1 (0.37) | ALDH1A1TDP1DPP8DPP9SIGMAR1 | |
| SCHEMBL7458556 | 0.85 | CCR5 (0.33) | ALDH1A1TDP1DPP8DPP9MAPT | |
| SCHEMBL7455832 | 0.84 | CCR2 (0.36) | ALDH1A1SIGMAR1CCR2MAPTHPGD | |
| SCHEMBL7456013 | 0.81 | SIGMAR1 (0.40) | ALDH1A1TDP1DPP8DPP9SIGMAR1 | |
| SCHEMBL7454249 | 0.80 | CCR2 (0.45) | DPP8DPP9SIGMAR1CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882728-B1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO CO (JP) | 2002-09-04 | — | — | EP | disclosed |
| US-6090802-A | BACTERICIDE | SANKYO COMPANY, LIMITED (JP) | 2000-07-18 | — | — | US | disclosed |
| EP-0882728-A1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1998-12-09 | — | — | EP | disclosed |