Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | B3GNT2 | Q9NY97 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7447106 | 0.80 | PDE4B (0.40) | PDE4BGRIN1GRIN2BLMNAB3GNT2 | |
| SCHEMBL7183756 | 0.76 | PDE4B (0.47) | PDE4BKCNH2LMNAB3GNT2MEN1 | |
| SCHEMBL7184379 | 0.72 | PDE4B (0.38) | PDE4BKCNH2LMNACA12CA9 | |
| SCHEMBL16593900 | 0.71 | MEN1 (0.61) | PDE4BKCNH2LMNASMN1; SMN2CA12 | |
| SCHEMBL7180232 | 0.69 | HSD11B1 (0.39) | PDE4BSMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL7180238 | 0.69 | HSD11B1 (0.39) | PDE4BSMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL7444613 | 0.64 | SMN1; SMN2 (0.43) | LMNASMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL18600696 | 0.62 | PTGS2 (0.39) | LMNASMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL18600693 | 0.62 | PTGS2 (0.39) | LMNASMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL7191692 | 0.62 | ALDH1A1 (0.49) | KCNH2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1196391-A1 | BENZIMIDAZOLONE DERIVATIVES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-17 | — | — | EP | disclosed |
| WO-2001005770-A1 | BENZIMIDAZOLONE DERIVATIVES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-01-25 | — | — | WO | disclosed |