Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 10/20 | 0.42 |
| ▸ | PDE4A | P27815 | 9/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6949924 | 0.86 | CCNE1 (0.35) | PDE4DPDE4APDE4BPDE4CKMT2A | |
| SCHEMBL7682613 | 0.86 | PDE4D (0.44) | PDE4DPDE4APDE4BPDE4CMEN1 | |
| SCHEMBL6949794 | 0.83 | HDAC1 (0.36) | PDE4DPDE4APDE4BPDE4CMEN1 | |
| SCHEMBL7458253 | 0.80 | PDE4A (0.38) | PDE4DPDE4APDE4BPDE4CKMT2A | |
| SCHEMBL7456776 | 0.78 | PDE4A (0.37) | PDE4DPDE4APDE4BPDE4CKMT2A | |
| SCHEMBL7460856 | 0.78 | PDE4A (0.36) | PDE4DPDE4APDE4BPDE4CKMT2A | |
| SCHEMBL7680123 | 0.75 | THRB (0.38) | PDE4DPDE4APDE4BPDE4CMEN1 | |
| SCHEMBL7460958 | 0.73 | GAA (0.40) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL6742425 | 0.71 | THRB (0.38) | PDE4DPDE4APDE4BPDE4CMEN1 | |
| SCHEMBL7459262 | 0.69 | EPHX1 (0.54) | MEN1KMT2AMAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002540193-A | — | — | 2002-11-26 | — | — | JP | claimed |
| EP-1165515-A1 | PYRIDINE-2,3-DICARBOXYLIC ACID DIAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2002-01-02 | — | — | EP | claimed |
| WO-2000058288-A1 | PYRIDINE-2,3-DICARBOXYLIC ACID DIAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2000-10-05 | — | — | WO | claimed |