Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.56 |
| ▸ | EGFR | P00533 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470683 | 0.89 | KDM4E (0.61) | PKMEGFRMAPTLMNAALDH1A1 | |
| SCHEMBL7474181 | 0.86 | MAPK1 (0.56) | EGFRMAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL7469700 | 0.85 | EGFR (0.54) | EGFRMAPTLMNAHTTALDH1A1 | |
| SCHEMBL8825813 | 0.85 | PKM (0.56) | PKMEGFRMAPTLMNAHTT | |
| SCHEMBL7528662 | 0.83 | EGFR (0.52) | EGFRMAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL7457697 | 0.83 | EGFR (0.62) | EGFRMAPTSMN1; SMN2 | |
| SCHEMBL7474806 | 0.82 | EGFR (0.52) | EGFRMAPTHTTALDH1A1KDM4E | |
| SCHEMBL7471567 | 0.82 | PIK3CD (0.62) | EGFRMAPTLMNAHTTRAB9A | |
| SCHEMBL7469664 | 0.82 | HTT (0.63) | EGFRMAPTHTTPIK3CDPIK3R1 | |
| SCHEMBL7467125 | 0.82 | EGFR (0.51) | EGFRMAPTLMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |