Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4813196 | 0.93 | KMT2A (0.34) | KMT2AKDM4EGAA | |
| SCHEMBL714018 | 0.88 | KMT2A (0.43) | KMT2ALMNACA12CA1CA2 | |
| SCHEMBL3141095 | 0.87 | KMT2A (0.45) | KMT2ALMNACA12CA1CA2 | |
| SCHEMBL7713694 | 0.87 | KMT2A (0.33) | KMT2AKDM4EGAA | |
| SCHEMBL698650 | 0.85 | KMT2A (0.40) | KMT2ALMNANR1I2AHR | |
| SCHEMBL7458930 | 0.85 | KMT2A (0.40) | KMT2ALMNACA12CA1CA2 | |
| SCHEMBL9428396 | 0.84 | KMT2A (0.42) | KMT2ALMNANR1I2AHR | |
| SCHEMBL7976903 | 0.82 | KMT2A (0.37) | KMT2ALMNA | |
| SCHEMBL11248292 | 0.82 | KMT2A (0.38) | KMT2ALMNA | |
| SCHEMBL6305531 | 0.81 | KMT2A (0.38) | KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8481726-B2 | Process for the preparation of sterically hindered nitroxyl ethers | BASF SE (DE) | 2013-07-09 | — | — | US | disclosed |
| US-8471031-B2 | Process for the preparation of sterically hindered nitroxyl ethers | BASF SE (DE) | 2013-06-25 | — | — | US | disclosed |
| US-20110160453-A1 | Process for the preparation of sterically hindered nitroxyl ethers | CIBA CORPORATION | 2011-06-30 | — | — | US | disclosed |
| EP-2035381-B1 | PROCESS FOR THE PREPARATION OF STERICALLY HINDERED NITROXYL ETHERS | BASF SE (DE) | 2010-12-29 | — | — | EP | disclosed |
| US-20100249401-A1 | Process for the preparation of sterically hindered nitroxyl ethers | BASF SE (DE) | 2010-09-30 | — | — | US | disclosed |
| EP-2035382-B1 | PROCESS FOR THE PREPARATION OF STERICALLY HINDERED NITROXYL ETHERS | BASF SE (DE) | 2009-11-18 | — | — | EP | disclosed |
| EP-2035382-A1 | PROCESS FOR THE PREPARATION OF STERICALLY HINDERED NITROXYL ETHERS | Ciba Holding Inc. (CH) | 2009-03-18 | — | — | EP | disclosed |
| EP-2035381-A1 | PROCESS FOR THE PREPARATION OF STERICALLY HINDERED NITROXYL ETHERS | Ciba Holding Inc. (CH) | 2009-03-18 | — | — | EP | disclosed |
| US-7390904-B2 | Hydrogen peroxide catalyzed process for the preparation of sterically hindered N-hydrocarbyloxyamines | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-06-24 | — | — | US | disclosed |
| WO-2008003602-A1 | PROCESS FOR THE PREPARATION OF STERICALLY HINDERED NITROXYL ETHERS | CIBA HOLDING INC. (CH) | 2008-01-10 | — | — | WO | disclosed |
| WO-2008003605-A1 | PROCESS FOR THE PREPARATION OF STERICALLY HINDERED NITROXYL ETHERS | CIBA HOLDING INC. (CH) | 2008-01-10 | — | — | WO | disclosed |
| EP-1644329-A1 | HYDROGEN PEROXIDE CATALYZED PROCESS FOR THE PREPARATION OF STERICALLY HINDERED N-HYDROCARBYLOXYAMINES | Ciba SC Holding AG (CH) | 2006-04-12 | — | — | EP | disclosed |
| US-20050014948-A1 | Hydrogen peroxide catalyzed process for the preparation of sterically hindered N-hydrocarbyloxyamines | CIBA SPECIALTY CHEMICALS CORP. | 2005-01-20 | — | — | US | disclosed |
| WO-2005005388-A1 | HYDROGEN PEROXIDE CATALYZED PROCESS FOR THE PREPARATION OF STERICALLY HINDERED N-HYDROCARBYLOXYAMINES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-01-20 | — | — | WO | disclosed |
| US-6166212-A | Process for the synthesis of N-(hydroxyalkoxy) substituted hindered amine stabilizers | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014948-A1 | Hydrogen peroxide catalyzed process for the preparation of sterically hindered N-hydrocarbyloxyamines | HAO2, SOD1, PPOX | KMT2A 924/4885LMNA 3323/4885CA12 1353/4885 |
| US-20100249401-A1 | Process for the preparation of sterically hindered nitroxyl ethers | PPOX, CBR1, CBR3 | KMT2A 2110/4885LMNA 2799/4885CA12 4189/4885 |
| US-20110160453-A1 | Process for the preparation of sterically hindered nitroxyl ethers | PPOX, CBR1, CBR3 | KMT2A 1911/4885LMNA 2306/4885CA12 3843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.