Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 4/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.33 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.33 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9574306 | 0.93 | ALDH1A1 (0.36) | SIGMAR1DPP8DPP9ALDH1A1LMNA | |
| SCHEMBL7453533 | 0.90 | CCR2 (0.36) | CCR2SIGMAR1DPP8DPP9ALDH1A1 | |
| SCHEMBL7453530 | 0.90 | CCR2 (0.36) | CCR2SIGMAR1DPP8DPP9ALDH1A1 | |
| SCHEMBL9574282 | 0.89 | ALDH1A1 (0.36) | SIGMAR1DPP8DPP9ALDH1A1LMNA | |
| SCHEMBL9574544 | 0.89 | ALDH1A1 (0.36) | SIGMAR1DPP8DPP9ALDH1A1LMNA | |
| SCHEMBL7453536 | 0.88 | SIGMAR1 (0.33) | CCR2SIGMAR1DPP8DPP9ALDH1A1 | |
| SCHEMBL8447430 | 0.87 | TPSAB1 (0.39) | DPP8DPP9ALDH1A1LMNATPSAB1 | |
| SCHEMBL8444908 | 0.87 | TPSAB1 (0.39) | DPP8DPP9ALDH1A1LMNATPSAB1 | |
| SCHEMBL8542239 | 0.87 | EPHX2 (0.35) | SIGMAR1DPP8DPP9ALDH1A1EPHX2 | |
| SCHEMBL8541702 | 0.87 | EPHX2 (0.35) | SIGMAR1DPP8DPP9ALDH1A1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882728-B1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO CO (JP) | 2002-09-04 | — | — | EP | disclosed |
| US-6090802-A | BACTERICIDE | SANKYO COMPANY, LIMITED (JP) | 2000-07-18 | — | — | US | disclosed |
| EP-0882728-A1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1998-12-09 | — | — | EP | disclosed |