Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9574544 | 1.00 | ALDH1A1 (0.36) | ALDH1A1LMNAEPHX2SIGMAR1DPP8 | |
| SCHEMBL9574306 | 0.96 | ALDH1A1 (0.36) | ALDH1A1LMNAEPHX2SIGMAR1DPP8 | |
| SCHEMBL9574341 | 0.93 | DPP8 (0.35) | ALDH1A1LMNADPP8DPP9RAB9A | |
| SCHEMBL9574214 | 0.93 | DPP8 (0.35) | ALDH1A1LMNADPP8DPP9RAB9A | |
| SCHEMBL8435826 | 0.90 | EPHX2 (0.38) | ALDH1A1LMNAEPHX2SIGMAR1DPP8 | |
| SCHEMBL7459238 | 0.89 | CCR2 (0.39) | ALDH1A1LMNAEPHX2SIGMAR1DPP8 | |
| SCHEMBL7453683 | 0.89 | SIGMAR1 (0.35) | ALDH1A1LMNAEPHX2SIGMAR1DPP8 | |
| SCHEMBL8447430 | 0.87 | TPSAB1 (0.39) | ALDH1A1LMNADPP8DPP9RAB9A | |
| SCHEMBL8444908 | 0.87 | TPSAB1 (0.39) | ALDH1A1LMNADPP8DPP9RAB9A | |
| SCHEMBL8542239 | 0.87 | EPHX2 (0.35) | ALDH1A1EPHX2SIGMAR1DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560613-A1 | Antimicrobial carbapenem derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1993-09-15 | — | — | EP | disclosed |