Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7576540 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL6927238 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL6929573 | 0.79 | CHRNB2 (0.30) | — | |
| Hydrochloric Acid SCHEMBL6926200 | 0.75 | — | — | |
| SCHEMBL8024838 | 0.73 | CHRNB2 (0.30) | — | |
| SCHEMBL27351242 | 0.72 | PDCD1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL3041072 | 0.72 | GPR3 (0.30) | — | |
| SCHEMBL27536916 | 0.70 | PDCD1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL8017225 | 0.70 | — | — | |
| SCHEMBL27351240 | 0.69 | HTR7 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991675-A4 | ETHYLENE ENHANCEMENT OF PROCESSES FOR SYNTHESIS OF HIGH MELTING THERMOPLASTIC ELASTOMERIC ALPHA-OLEFIN POLYMERS (PRE/EPE EFFECTS) | UNIV LELAND STANFORD JUNIOR (US) | 2002-07-03 | — | — | EP | disclosed |
| EP-0991675-A1 | ETHYLENE ENHANCEMENT OF PROCESSES FOR SYNTHESIS OF HIGH MELTING THERMOPLASTIC ELASTOMERIC $g(a)-OLEFIN POLYMERS (PRE/EPE EFFECTS) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2000-04-12 | — | — | EP | disclosed |
| WO-1998057996-A1 | ETHYLENE ENHANCEMENT OF PROCESSES FOR SYNTHESIS OF HIGH MELTING THERMOPLASTIC ELASTOMERIC α-OLEFIN POLYMERS (PRE/EPE EFFECTS) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD, JR. UNIVERSITY (US) | 1998-12-23 | — | — | WO | disclosed |