Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | PPID | Q08752 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5941081 | 0.84 | PIN1 (0.56) | ALDH1A1PPIDSMN1; SMN2PIN1LMNA | |
| SCHEMBL9686760 | 0.83 | PIN1 (0.53) | ALDH1A1PPIDSMN1; SMN2PIN1LMNA | |
| SCHEMBL15173708 | 0.81 | PIN1 (0.54) | ALDH1A1PPIDSMN1; SMN2PIN1LMNA | |
| SCHEMBL3213534 | 0.81 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2PIN1LMNAPOLB | |
| SCHEMBL24339819 | 0.81 | PIN1 (0.51) | ALDH1A1PPIDSMN1; SMN2PIN1LMNA | |
| SCHEMBL16109415 | 0.81 | CTSS (0.62) | ALDH1A1PPIDSMN1; SMN2PIN1 | |
| SCHEMBL7745572 | 0.80 | CTSL (0.53) | ALDH1A1PPIDSMN1; SMN2PIN1LMNA | |
| SCHEMBL15173707 | 0.80 | PIN1 (0.53) | ALDH1A1PPIDSMN1; SMN2PIN1LMNA | |
| SCHEMBL691909 | 0.80 | SMN1; SMN2 (0.56) | ALDH1A1SMN1; SMN2PIN1LMNAPOLB | |
| SCHEMBL22144166 | 0.80 | PIN1 (0.50) | ALDH1A1PPIDSMN1; SMN2PIN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0718290-B1 | Carboxyalkyl heterocyclic derivatives | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 2002-04-17 | — | — | EP | disclosed |
| US-5912261-A | ANTIDIABETIC AGENTS | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1999-06-15 | — | — | US | disclosed |
| EP-0718290-A1 | Carboxyalkyl heterocyclic derivatives | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1996-06-26 | — | — | EP | disclosed |