Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | C1R | P00736 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | GUSB | P08236 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7812699 | 0.81 | ALDH1A1 (0.52) | ALDH1A1RAB9AMEN1MAPTKMT2A | |
| SCHEMBL7464693 | 0.76 | ACHE (0.51) | MEN1KMT2AACHEADORA2AKDM4E | |
| SCHEMBL7464351 | 0.76 | ACHE (0.51) | MEN1KMT2AACHEADORA2AKDM4E | |
| SCHEMBL7458826 | 0.72 | TP53 (0.60) | ALDH1A1RAB9AMEN1MAPTKMT2A | |
| SCHEMBL7464639 | 0.72 | TP53 (0.60) | ALDH1A1RAB9AMEN1MAPTKMT2A | |
| SCHEMBL7122711 | 0.70 | NQO2 (0.59) | ALDH1A1RAB9AMEN1MAPTKMT2A | |
| SCHEMBL8947495 | 0.70 | EGFR (0.73) | ALDH1A1RAB9AMEN1MAPTKMT2A | |
| SCHEMBL3417492 | 0.68 | EGFR (0.76) | ALDH1A1RAB9AMEN1MAPTKMT2A | |
| SCHEMBL23271812 | 0.68 | MAPT (0.66) | ALDH1A1RAB9AMEN1MAPTKMT2A | |
| SCHEMBL9814172 | 0.68 | PDE3B (0.51) | ALDH1A1MAPTSMN1; SMN2C1RADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0785191-B1 | FUSED INDAN DERIVATIVES AND SALTS THEREOF | TAIHO PHARMACEUTICAL CO LTD (JP) | 2002-10-23 | — | — | EP | disclosed |
| US-5763453-A | ANTITUMOR AGENTS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| EP-0785191-A1 | FUSED INDAN DERIVATIVES AND SALTS THEREOF | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |