Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.42 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.42 |
| ▸ | MCOLN1 | Q9GZU1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HPN | P05981 | 1/20 | 0.37 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.37 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468510 | 0.81 | KCNA3 (0.38) | ALDH1A1DRD2CCR5SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8891381 | 0.74 | CCR1 (0.44) | KMT2A | |
| SCHEMBL8341471 | 0.69 | MMP3 (0.50) | MCOLN2MCOLN3MCOLN1ALDH1A1MMP3 | |
| SCHEMBL8344718 | 0.67 | MMP3 (0.50) | MCOLN2MCOLN3MCOLN1MMP3HPN | |
| SCHEMBL1338231 | 0.67 | CCR10 (0.55) | ALDH1A1HTTGAAKDM4ESMN1; SMN2 | |
| SCHEMBL7460709 | 0.65 | MCHR1 (0.55) | DRD2HTR1AHTR1BHTR2AHTR7 | |
| SCHEMBL1664838 | 0.64 | HTR7 (0.45) | ALDH1A1HTTDRD2HTR1AHTR1B | |
| SCHEMBL9512288 | 0.64 | KMT2A (0.49) | ALDH1A1HTTHTR2AGAAKMT2A | |
| SCHEMBL9511087 | 0.63 | CYP2D6 (0.47) | ALDH1A1HTTHTR2AGAAKDM4E | |
| SCHEMBL9511108 | 0.63 | KMT2A (0.48) | ALDH1A1HTTHTR2AGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |
| EP-0712845-B1 | Amine compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-10-17 | — | — | EP | disclosed |
| US-5633248-A | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS, DIARYLALKYLIDENEDIAMINES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-05-27 | — | — | US | disclosed |
| EP-0712845-A1 | Amine compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-22 | — | — | EP | disclosed |