Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9511108 | 0.96 | KMT2A (0.48) | KMT2AMEN1CNR1CNR2SMN1; SMN2 | |
| SCHEMBL9511087 | 0.89 | CYP2D6 (0.47) | KMT2AMEN1CNR1CNR2SMN1; SMN2 | |
| SCHEMBL9462804 | 0.71 | SMN1; SMN2 (0.81) | KMT2AMEN1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL27747982 | 0.71 | ALDH1A1 (0.44) | KMT2AMEN1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL25525586 | 0.70 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1LMNACYP2C9 | |
| SCHEMBL9511082 | 0.70 | HTR7 (0.67) | KMT2ASMN1; SMN2ALDH1A1HTTLMNA | |
| SCHEMBL2228232 | 0.69 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1GAALMNACYP2C9 | |
| SCHEMBL11938950 | 0.68 | OPRM1 (0.68) | OPRD1OPRM1OPRK1OPRL1CHRM2 | |
| Hydrochloric Acid SCHEMBL8572302 | 0.68 | OPRM1 (0.51) | KMT2AMEN1CNR1CNR2ALDH1A1 | |
| SCHEMBL9512269 | 0.68 | HTR7 (0.60) | KMT2ASMN1; SMN2ALDH1A1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330065-B1 | Sulfonamide compounds | KOWA CO (JP) | 1993-11-10 | — | — | EP | claimed |
| US-4948892-A | Sulfonamid compound useful for treating cardiovascular disorders | KOWA COMP., LTD. (JP) | 1990-08-14 | — | — | US | claimed |