Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.52 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 5/20 | 0.51 |
| ▸ | BACE1 | P56817 | 5/20 | 0.51 |
| ▸ | BCHE | P06276 | 4/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.49 |
| ▸ | TACR1 | P25103 | 2/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | FABP6 | P51161 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8396136 | 0.94 | HTR3E (0.51) | CARM1PRMT6GRIN2BACHEBACE1 | |
| SCHEMBL20794929 | 0.85 | ACHE (0.50) | ACHEBACE1BCHECHRM1SLC6A2 | |
| SCHEMBL14388279 | 0.84 | ACHE (0.49) | CARM1PRMT6GRIN2BACHEBACE1 | |
| SCHEMBL20794844 | 0.84 | CHRM1 (0.57) | ACHEBACE1BCHECHRM1CHRM2 | |
| SCHEMBL8253600 | 0.83 | ACHE (0.48) | CARM1PRMT6GRIN2BACHEBACE1 | |
| SCHEMBL3359640 | 0.82 | CARM1 (0.58) | CARM1PRMT6ACHEBACE1CHRM1 | |
| SCHEMBL13538303 | 0.82 | CARM1 (0.43) | CARM1PRMT6ACHEBACE1BCHE | |
| SCHEMBL6997039 | 0.82 | ACHE (0.58) | GRIN2BACHEBACE1BCHECHRM2 | |
| SCHEMBL6997045 | 0.82 | ACHE (0.58) | GRIN2BACHEBACE1BCHECHRM2 | |
| SCHEMBL13253002 | 0.80 | KDM1A (0.47) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242421-A1 | 4-[ARYL(8-AZABICYCLO[3.2.1] OCTAN-3-YL)] AMINOBENZOIC ACID DERIVATIVES | Ortho-McNeil Pharmaceutical, Inc. (US) | 2002-09-25 | — | — | EP | disclosed |
| EP-0690055-B1 | Stereoselective process for making endo-tropanamine and like compounds | LILLY CO ELI (US) | 2001-11-14 | — | — | EP | disclosed |
| US-6306876-B1 | DRUGS WITH DIASTERIOMERS | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2001-10-23 | — | — | US | disclosed |
| WO-2001046191-A1 | 4-[ARYL(8-AZABICYCLO[3.2.1]OCTAN-3-YL)]AMINOBENZOIC ACID DERIVATIVES | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-06-28 | — | — | WO | disclosed |
| US-5625065-A | Stereoselective process for making endo-tropanamine and like compounds | ELI LILLY AND COMPANY (US) | 1997-04-29 | — | — | US | disclosed |
| EP-0690055-A1 | Stereoselective process for making endo-tropanamine and like compounds | ELI LILLY AND COMPANY (US) | 1996-01-03 | — | — | EP | disclosed |