Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 8/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 8/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.48 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | SMO | Q99835 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6944610 | 0.90 | ADRB3 (0.53) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7560376 | 0.88 | LMNA (0.56) | LMNAMEN1KMT2AKDM4EMITF | |
| SCHEMBL7836521 | 0.86 | LMNA (0.53) | LMNAMEN1KMT2AKDM4EMITF | |
| SCHEMBL7469004 | 0.78 | ADRB3 (0.52) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7473044 | 0.78 | ADRB3 (0.52) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7470650 | 0.78 | LMNA (0.46) | LMNAMEN1KMT2AKDM4EMITF | |
| SCHEMBL7461831 | 0.78 | LMNA (0.46) | LMNAMEN1KMT2AKDM4EMITF | |
| SCHEMBL5207745 | 0.78 | ADRB1 (0.46) | LMNAMEN1KMT2AKDM4EMITF | |
| SCHEMBL7467859 | 0.77 | LMNA (0.45) | LMNAMEN1KMT2AKDM4EMITF | |
| SCHEMBL6139555 | 0.77 | LMNA (0.42) | LMNAMEN1KMT2AKDM4EMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087961-B1 | PHENOXYLPROPANOLAMINES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SANOFI SYNTHELABO (FR) | 2002-08-14 | — | — | EP | disclosed |